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Is Autophagy the Key to Unlocking Eternal Youth?

by Cecilia Lodi on March 31, 2022

Aging is natural occurrence experienced by all living organisms. It is referred to as the deterioration of our cells’ functioning due to damages they accumulated over time. For centuries, aging has become an important biological, demographic and socio-economic issue all over the world.

As a natural physiological process, aging is characterized by:

  • a progressive loss of physiological integrity
  • loss of cellular homeostasis and balance 
  • Innate immunity dysfunctions 
  • metabolic disorders 
  • cardiovascular diseases

From tribal healers and apothecarists of ancient civilizations, to scientists and experts of the modern world, different theories about aging have emerged and the single question  

Recent studies have pointed to the decline in the autophagic capacity of the body’s cells. For those unfamiliar with the term, Autophagy’s literal meaning is “self-devouring”. And while it sounds like a horror movie that you don’t want to happen inside your body, Autophagy is your body’s way of cleaning out damaged cells, and recycling residual proteins, in order to regenerate newer, healthier cells. 

What happens when we age is that the autophagic process declines and this results in the build-up of dysfunctional mitochondria and reactive oxygen species (ROS) that expose our cells and tissues to a very toxic environment, which then increases the individual’s risk of acquiring age-related diseases. 

Following this thread, the billion-dollar question that really matters is, ‘What stimulates Autophagy?’ If this natural phenomenon of self-regulation and constant self-renewal is the key to longevity and perpetual youth, how can we keep it going? 



Effective ways to Boost Autophagy (Science-based)

Growth Hormone

Growth Hormone acts through its receptor in the liver to activate autophagy, preserve triglycerides, enhance gluconeogenesis, and prevent hypoglycemia, especially when the body is subjected to calorie restriction.

One way to optimize one’s growth hormone levels for anti-aging purposes is by administering HGH injections, which is all the rave in sophisticated anti-aging clinics and rejuvenation spas throughout the globe.

Elite Bioscience Biotropin® is a bio-identical HGH using recombinant technology and has the endogenous 191 amino acid form making it effective and stable. 

With a minimal daily dose of 2-3 IU, Biotropin® HGH replenishes HGH levels needed for simultaneous tissue repair, cell replacement, and continuous collagen synthesis thus efficiently diminishing the undesirable consequences of ageing. 



Ghrelin, a unique 28-amino-acid peptide, is a relatively novel multifaceted molecule that has been found to exert a plethora of physiological effects. Some of the physiological effects of ghrelin are:

  • induces appetite
  • promotes the use of carbohydrates as a source of fuel 
  • stimulates release of growth hormone
  • improves cardiac performance
  • decreases blood pressure 


Moreover, ghrelin makes the skeletal muscle more excitable, stimulates its regeneration following injury, and promotes wound healing. Ghrelin protects the body by different mechanisms, including inhibition of unwanted inflammation and induction of autophagy. 


Definitely, having a clear understanding of ghrelin’s actions in each organ system has beneficial anti-aging implications. So how does one enhance the body’s ghrelin levels? 


This can be done through fasting, which works well for some individuals who are used to abstaining from food for 16 to 20 hours, or days on end. If you are not that kind of person, another way is to take a supplement that augments the action of ghrelin.


GH Pep® MK-677 is taken orally and mimics the action of ghrelins. It is what you call a ghrelin-mimetic. It basically mimics all the actions of ghrelin, which includes sending signals to the brain to facilitate the pulsatile release of Human Growth Hormone (HGH). 


What’s unique about this compound is that research studies discovered that through the mediation of your body’s growth hormone, GH Pep® MK-677  stimulates the production of Insulin-Like Growth Factor 1 (IGF-1). IGF-1  works to sustain the healthy functioning of our body by supporting the growth of bones and other tissues, and promoting the production of lean muscle mass- thus delaying the signs and symptoms of advanced aging. IGF-1 also plays a role in non-growth activities, such as glucose and lipid metabolism for the constant nourishment of the body’s cells and tissues.