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The Best Post-Cycle Regimen to Complement TRT

by Cecilia Lodi on September 21, 2022

Bio-identical hormone replacement with high quality and medical-grade testosterone and human growth hormone is the cornerstone of most Anti-Aging programs, bringing back vitality and reducing the risk of developing diseases and symptoms related to aging such as cardiovascular diseases, obesity, dementia, sexual dysfunction, chronic fatigue, and osteoporosis.

Through Hormone therapy cycles under the close supervision of our anti-aging health specialists, we treat symptoms such as:


  • decreased motivation
  • irritability and mood changes
  • decreased stamina
  • brain fog/memory loss
  • insomnia
  • weight gain
  • decreased muscle mass with increased body fat
  • decreased sex drive
  • sub-par workout performance, and
  • slow recovery

Overall, we alleviate the sense of “getting old” as we bring clients back to their energetic, youthful self.

But when you’re fully focused on optimizing your testosterone treatment, supported by your nutrition and lifestyle habits, it’s all too easy to give little thought it what could essentially be a fundamental aspect of your hormone therapy: Post-cycle therapy (PCT).

A testosterone treatment course completely changes the functioning of your natural hormone system. You might completely stop making natural testosterone once you reach supra-physiologic levels in the body over long periods of time.
Post-cycle therapy (PCT) is a crucial step that requires just as much consideration and preparation as your hormone therapy sessions.

It requires taking a number of prescription drugs that you may or may not have easy access to, and it also necessitates that you comprehend how they all function and the ideal combination, dose, and duration for your post cycle therapy plan.

Everything you need to know about post cycle therapy and how to apply it to your lifestyle routine is included in this guide. Post-cycle therapy should be given the same emphasis as all other aspects of your testosterone sequence regimen in order to improve results and safeguard your health. And this is where administering HCG injections becomes crucial. You can use HCG in two ways:

  1. During testosterone treatment, to further optimize testosterone levels.
  2. After TRT, to prevent complete hormone shutdown that may happen due to the negative feedback mechanism of the HPT Axis.


One of the main goals of post cycle therapy is to restore your hormone balance. Men who take testosterone may use BIO-HCG® to help prevent or reverse some of the side effects of TRT, particularly Testosterone shutdown, which can lead to gonad shrinkage, sexual dysfunction, and infertility.


How does BIO-HCG® stimulate testosterone production?

In men, HCG functions similarly to luteinizing hormone (LH). Studies demonstrate that Human Chorionic Gonadotropin or HCG stimulates Leydig cells in the testicles, resulting in testosterone production. It also stimulates sperm production through structures in the testicles known as seminiferous tubules. Fertility is restored as BIO-HCG® stimulates the testicles to produce testosterone and sperm, and the testicles grow in size over time.


Now, the other component of this protocol is the addition of an Aromatase Inhibitor. Testosterone can quickly convert to estrogen, and because estrogen is primarily a female hormone, it can cause breast tissue growth in men undergoing testosterone therapy. The medical term for this condition is gynecomastia.

High estrogen levels can also cause loss of libido, bloating, mood swings, and water retention. The main reason people use Aromatase Inhibitors after a treatment course is to avoid these side effects when free circulating testosterone is at its peak and can massively convert to estradiol.


How do Aromatase Inhibitors function?

Aromatase is the major liver enzyme responsible for this testosterone-to-estrogen conversion. Men can take an aromatase inhibitor to prevent the aromatization process. Re-Charge® (Arimistane) is a high-quality, lab-certified aromatase inhibitor that is recommended to be taken at a daily dose of 25 mg to effectively block this biochemical transformation.


The main benefits of using Aromatase Inhibitors are:

  • Blocking the aromatase enzyme to stop the conversion of androgens to estrogens
  • Increasing testosterone by lowering estrogen
  • Preventing gynecomastia
  • Reducing fluid retention, mood swings, and libido loss
  • Mitigating the estrogenic effects of HCG




Ancillaries for PCT


The Protocol:

1. During Testosterone Therapy, to maximize androgen hormone levels, Inject .5 ml or 1250 IU of BIO-HCG® every 2nd or 3rd day (2x/week). For example, .5 ml administered every Monday and Thursday during TRT course. Stop once TRT is finished.


After Testosterone Therapy, to boost endogenous Testosterone production and avoid shutdown, thus preventing testicular atrophy and other undesirable effects. Inject .5 ml or 1250 IU of BIO-HCG® every 2nd or 3rd day (2x/week). For example, .5 ml administered every Monday and Thursday. Administer post-TRT for 2-4 weeks.

2.  Post-TRT, to prevent aromatization to estradiol, take Re-Charge® (Arimistane) at an oral dose of 1 ml equivalent to 25 mg once a day for 4-6 weeks. Re-Charge® can be taken with BIO-HCG® injection.