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Supplier: Elite Bioscience®
Product: Sermorelin® x 1 vial
Active Ingredient: Sermorelin, GRF 1-29, (C149H246N44O42S)
Half-Life: Sermorelin has an approximate half-life of 11-12 minutes after either intravenous or subcutaneous administration.
Dosage and packing: 5 mg Sermorelin® lyophilized powder in a multi-dose glass vial
Sermorelin® is the pharmaceutical version of growth hormone releasing hormone (GHRH), the primary hormone responsible for stimulating natural growth hormone production. It is classified as a growth hormone secretagogue, a substance that encourages enhanced growth hormone secretion from the pituitary gland. It is also known as growth hormone releasing factor and GRF 1-29.
Sermorelin is also known as GRF 1-29 or Sermorelin acetate, which are both variations of its chemical name. The substance is a peptide counterpart of a hormone called growth hormone-releasing hormone (GHRH), for which synthesis declines with advancing years. It is used medically as an anti-ageing treatment with the ultimate effect of increasing the body’s endogenous growth hormone secretion (HGH).
Research has shown that Sermorelin works by supporting the pituitary gland's efficient functioning. This gland's job is to secrete hormones that regulate the body's physiological processes, including growth, pregnancy, delivery, and metabolism, among other things.
Sermorelin functions similarly to the body's natural GHRH by binding to the growth hormone releasing hormone receptor (GHRHr) in the anterior pituitary gland. There, it starts to boost the creation of endogenous IGF-1 and stimulate growth hormone production. Sermorelin's favourable influence on growth hormone output is moderated by a negative feedback mechanism started by somatostatin, the endogenous hormone also known as growth hormone inhibitory hormone, because it behaves similarly to GHRH (GHIH).
The prevention of severe, harmful growth hormone levels in the body and the replication of more natural patterns of fluctuation in growth hormone concentrations are only two of the numerous beneficial impacts that this triggers.
By preserving the hypothalamic-pituitary-somatotropic axis, Sermorelin natural action mechanism avoids the normal hormonal production shutdown that results from HGH replacement. Sermorelin has also been demonstrated to increase the duration of restorative slow wave sleep, boosting sleep-related growth hormone secretion while decreasing cortisol synthesis (a catabolic stress hormone).
There are hundreds of online vendors that sell Sermorelin and finding a supplier you can trust, can sometimes prove to be daunting.
Sermorelin® from Elite Bioscience is a premium quality, bio-identical ester of Testosterone. Our state-of-the-art labs individually vacuum seal sterile vials of 99.9% Pure Pharmaceutical Grade, active, lyophilized Sermorelin.
We strongly believe in bringing you quality Sermorelin that is free from impurities, additives and contaminants that are present in cheap versions flooding the current market. We also publish certificates of analysis (COA) from a third-party tester that are onsite to prove that we only ship pure, medical-grade Sermorelin.
Sermorelin is a sterile, non-pyrogenic, lyophilized powder intended for subcutaneous injection after reconstitution with Sodium Chloride Injection, USP or bacteriostatic water.
Sermorelin has been demonstrated in recent scientific studies to stimulate HGH production and support fat loss. Those who are obese or have problems losing weight may also have hormone levels that are lower than those who are at a healthy weight, according to clinical studies. Sermorelin can therefore help overweight adults by boosting HGH levels and facilitate fat reduction.
Low hormone levels are usually associated with mood problems. Conversely, when HGH levels are brought back to normal, people's energy and mood are enhanced. Sermorelin has shown promise in treating anxiety and depression in a number of human clinical trials.
Increased libido and sexual desire have also been connected to Sermorelin peptide levels above a particular threshold, according to studies. This is significant since it has been shown that healthy levels of growth hormone (GH) are associated with a healthy sex drive. Unrestricted blood flow is necessary for both sexes to maintain their highest levels of sexual arousal and performance.
The goal of Sermorelin therapy is to help your pituitary gland produce more HGH naturally. This can reverse or prevent many of the problems that develop due to HGH deficiency.
Before puncturing the rubber vial stopper with the needle, clean it with an antiseptic solution to ward off potential contamination. Sermorelin should only be delivered with sterilised, disposable syringes and needles.
Inject the diluent (bacteriostatic water or Sodium Chloride Injection, USP) into the vial of Sermorelin, aiming the liquid against the glass vial wall. Gently rotate the vial until all of the contents have dissolved. If there are any discernible particles or if the reconstituted solution is hazy, do not administer Sermorelin.
The volume of the syringes should be kept to a minimum (insulin syringe is recommended) so that the recommended amount may be accurately pulled from the vial.
Dose amount: 100 to 1000 micrograms (0.10mg to 1.0mg)
Dose Frequency: 1 - 3 times daily
Sermorelin may be taken once daily, just before night, or in two to three smaller doses spread out throughout the day. Both methods of delivery have been established in clinical research to be successful and to produce favourable outcomes.
Although Sermorelin has a half-life of up to 20 minutes, it has been demonstrated that for two hours following injection, it can promote an very high release of growth hormone. It has been found that protocols administering three daily doses of as little as 100 mcg (0.10 mg) per administration significantly boosted the release of human growth hormone and IGF-1.